In order to evaluate the effects of therapeutic toothpastes containing sanguinaria extract and sodium fluoride on the inhibition of dental. plaque formation, the authors had examined the oral status of 50 students aged twentieth. Then, they were given with cosmetic toothpaste and therapeutic toothpaste in due sequence. At the same time, all students were given with straight handled mixed bristled toothbrush and directed to brush teeth with offered toothbrush and toothpaste.
The patient hygiene performance were examined in the 7th day, after that they changed their toothpaste to another one. So, each of them could use 2 toothpastes for 7 days respectively.
On the other hand, to evaluate the reducing. effects of dentifrice containing sanguinaria extract and sodium fluoride on the numbers of streptococci, 20 adults aged twentieth were estimated. Before beginning the, experiments, the subject gargled their mouth with 0.1% peptone solution and after that brushed teeth with offered toothbrush and dentifrice containing sanguinaria extract for 1 week and 3 weeks. To collect data, every subjects rinsed their mouth with 0.1% pepton solution, the rinsing solutions were inoculated on MSB agar plate. After 3 days anaerobic incubation, under the conditions of 10% H2- 10% Co2 80% N2 , the colony forms. were identified under the microscope and 9 biochemical tests were undertaken.
Thereafter, the data was compared statistically and discussed. The results obtained were as follows:
1. Therapeutic toothpastes containing sanguinaria extract and sodium fluoride inhibited plaque formation more effectively than cosmetic toothpaste (P<0.05).
2. After the use of therapeutic toothpaste containing sanguinaria extract and sodium fluoride, the numbers of S. mutans & S. mitis were decreased at 3 weeks (p<0.05).
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